ABSTRACT
Background: Breathox is a sodium chloride inhaler. Increase of the airway salinity has been proposed to reduce the symptomatic stage of a respiratory viral infection. Objective(s): to evaluate the effectiveness of nasal and inhaled sodium chloride therapy through Breathox on mild COVID-19 symptoms in patients >= 18 years-old compared to usual care. Method(s): a pilot, open, randomized clinical trial, including 100 patients with confirmed and symptomatic COVID-19 within 10 days of symptom onset. All patients received standard of care (SOC), i.e. antipyretic or analgesic. Breathox was administered as two oral inhalations and one nasal instillation in each nostril at each administration with 2mg per inhalation. Patients were randomized 1:1:1 into three groups: Group 1(G1): SOC + Breathox 10 times daily for 10 days;Group 2(G2): SOC + Breathox five times daily for 10 days;Group 3(G3): SOC. Recovery time for symptoms, such as cough was assessed. Result(s): In total 100 of 103 screened patients were included from December 1 2021 to March 03 2022. Of those, 33 from G1 and G3, and 32 from G2 completed the study. Mean age was 40.4/42.2/40.6 years old for G1, G2 and G3, (p=0.96). No patients were hospitalized or died during the study. Time to cough resolution was reduced in G1 (2.8+/-0.66 days) and G2 (2.4+/-0.66 days) compared to G3 (5.39+/-0.79 days) (p=0.001), with a hazard ratio (HR) for G2 of 2.17 (Confidence interval 1.17-4.04) and G3 of 2.01 (1.06-3.81) compared to SOC. Conclusion(s): ten days of Breathox use halved the time for resolution of COVID-19-induced cough.
ABSTRACT
The outbreak of COVID-19 caused a major international public health crisis and led to the imposition of social distancing measures to contain the spread of the virus. In this context, the use of telehealth skyrocketed as the only way to deliver healthcare to patients during a lockdown was remotely. The countries of Latin America and the Iberian Peninsula were severely hit by the pandemic and the prospects and challenges associated with widespread adoption of telehealth are unique. The goal of this systematic literature review is to explore how telehealth has been used during the pandemic to prevent, diagnose, treat and control diseases in Ibero-America. Thus, we sought to identify the main keywords, themes, theoretical frameworks and methodologies used by researchers in this area. We used several tools for bibliographic management like Rayyan, VOSViewer and NVIVO and followed the PRISMA protocol. Our analysis of themes showed the existence of 3 nodes within the literature: students, teachers and education. After searching in 6 databases, 1826 articles were found. After excluding the duplicates (231 articles), we screened and read the titles and s of 1595 articles. Only 119 articles met the inclusion criteria. Finally, after a full-text analysis, a final sample of 106 articles was selected for analysis. Spain and Brazil are the countries who have produced the greatest volume of research in the region. The public sector is the largest funder of research on this topic by far especially at national level. Our findings show that the research output in the region of Ibero-America (Latin America and Iberia) on this topic is still relatively small when compared to regions like North America. Copyright © 2023 by Author/s and Licensed by IADITI.
ABSTRACT
This study aimed to understand the meaningful attitudes of alcoholic men and their expressions of feelings in the face of family and community interactions in times of the COVID-19 pandemic. This is a qualitative, descriptive, exploratory study, based on the Oral History of Life method. The participants of this study were five men who experience alcoholism, living in a municipality in the state of Bahia, accompanied by the Psychosocial Care Center for alcohol and other drugs. A semi-structured interview was used to collect information, from March to April 2021, through videoconferences through the Google Meet Digital Platform. The content of the oral reports was analyzed using a content analysis technique. It was observed that the significant attitudes of the alcoholic man were impacted by the unfolding of the pandemic, mainly due to the adoption of sanitary measures, such as social distancing. Some expressions of feelings were also identified of these men facing family and community interactions during the pandemic, such as fear, distrust, and affective insecurity, and social exclusion, in addition to expressions such as faith, gratitude, and hope. The participants' discourses expressed attitudes of changes in social life and habits during this pandemic period, including the use of masks and gel alcohol in addition to the decrease in alcohol consumption for most of them. Therefore, the symbolic interactions arising from the pandemic scenario promoted protective attitudes that encompass self-care and collective care, in addition to interactions marked by family conflicts. © 2022 Centro Universitario Sao Camilo. All rights reserved.
ABSTRACT
Introduction Vaccination is the primary pharmacological measure to reduce SARS-CoV-2 transmission and its complications. Timely information on vaccines effectiveness in a context of novel variants of concern (VOC) emergence is essential for public health policies. This study aimed to provide a measure of comparative vaccine effectiveness between Omicron (BA.1) and Delta (B.1.627.2) VOC according to vaccination exposure (complete primary regimen or booster dose) for Portuguese population aged 12 or more years old using routinely collected data from electronic health records. Methods We used a case-case study design linking national electronic vaccination registry and surveillance data on 13,134 SARS-CoV-2 RT-PCR laboratory-confirmed cases notified in Portugal during weeks 49-51 of 2021. Notified cases were classified as Omicron or Delta based on whole-genome sequencing or S-gene Target Failure (SGTF) status using the RT-PCR TaqPath™ Covid 19 CE IVD Kit (Thermo Scientific™) assay. The odds of vaccination was compared between Omicron cases and Delta cases using logistic regression adjusted for age group, sex, region and week of diagnosis and laboratory of origin. Results The odds of vaccination were higher in laboratory-confirmed cases infected by Omicron (BA.1) VOC compared to Delta (B.1.627.2) VOC for both complete primary vaccination (Odds ratio (OR)=2.1;95% Confidence Interval (95%CI): 1.8 - 2.4) and booster dose (OR = 5.2;95%CI: 3.1 - 8.8), indicating vaccine effectiveness reduction against Omicron. Conclusions We found significantly higher odds of vaccination in Omicron cases compared to Delta, suggesting lower effectiveness of the primary vaccination and the booster dose in preventing infections by Omicron. Case-case study design has proven to be feasible approach to rapidly compare vaccine effectiveness between VOC in context of novel VOC emergence to timely inform public health stakeholders. Key messages • Reduction of vaccine-induced protection against SARS-COV-2 infection with the Omicron compared to Delta after primary and booster vaccination. • Continuous monitoring of COVID-19 vaccine effectiveness is essential to support public health policies in context of novel VOC emergence.
ABSTRACT
Objective: to analyze the relationship between the Burnout dimensions and the work resilience of intensive care Nursing professionals in the COVID-19 pandemic in four hospitals from southern Brazil. Method: this is a multicenter and cross-sectional study, composed of 153 nurses and nursing technicians of the Intensive Care Units. Sociodemographic, health and work-related questions were collected, and the Maslach Burnout Inventory and Resilience at Work Scale 20 instruments were applied. The data were submitted to descriptive analysis and to bivariate and partial correlations (network analysis). Results: work resilience presented an inverse correlation to emotional exhaustion (r=-0.545;p=0.01) and depersonalization (r=-0.419;p=0.01) and a direct one to professional achievement (r=0.680;p=0.01). The variable with the greatest influence on the correlation network was the perception of the impact of the pandemic on mental health. Conclusion: resilience interferes in the emotional exhaustion and low professional achievement domains of Burnout. Emotional exhaustion is conducted through minor psychological disorders, with an impact on the workers’ physical and mental health variables. The development of institutional resilience should be encouraged in order to moderate the illness. © 2022 Revista Latino-Americana de Enfermagem.
ABSTRACT
Objective: to identify psychological alterations in nursing professionals belonging to and not belonging to the risk group for complications of COVID-19. Methods: multicenter cross-sectional study with 845 nursing professionals from four hospitals in southern Brazil between August and October 2020. Data collection was performed through an electronic form containing the Self-Reporting Questionnaire and the Maslach Burnout Inventory. Descriptive and inferential statistics were used. Results: among the 845 participants, 214 belonged to the risk group. These presented higher means in emotional exhaustion and depersonalization scores (p<0.05), and higher percentages of Minor Psychiatric Disorders (55.2%). Minor Psychiatric Disorders and being part of institution B explained in 10.0% the variability of Professional Achievement. Minor Psychiatric Disorders, use of medications, impact on mental health and being part of institutions A, B and C explained in 38.7% the variability of Emotional Exhaustion. Minor Psychiatric Disorders, impact on mental health and being part of institutions A and B explained in 23.1% the variability of Depersonalization. Conclusions: the risk group presented greater exposure to psychological alterations. The regression model did not identify a difference between being or not of the risk group regarding Burnout Syndrome. The study contributes to the planning of protective labor interventions within institutions and public health policies, aiming to reduce possible factors related to the involvement of Burnout Syndrome and Minor Psychiatric Disorders. © 2022, Universidade Federal de Santa Catarina. All rights reserved.
ABSTRACT
This article pairs journalism studies and social psychology to investigate, with a quantitative method, audience perceptions of news media in the initial stages of the Covid-19 pandemic in Brazil by verifying the relations among media credibility, subjective well-being (SWB), and fear of missing out (FoMO). All told, 306 Brazilians took part in this study, answering a questionnaire to elicit demographic data, perceptions of media credibility, and behavioral characteristics. The findings revealed high averages of measures of news media credibility, with over 70% of respondents evaluating the work of the press as excellent or good. People with higher averages of negative affects tended to perceive the news media as more reliable. Furthermore, individuals who reported fear of missing out on the news during Covid-19 experienced more negative affect, and attributed greater credibility to news media. These findings show that in a time of fear and uncertainty, citizens seem to trust solid institutions more, accepting their reports less critically. We also found that unknown risks can attract attention more than regular events, tending to keep vigilance on specific news. Future studies can add additional measures of FoMO and use more diverse samples in different contexts.
ABSTRACT
Conceptually aligned with the epistemologies of digital journalism, and in line with the definition of ‘total journalism’, this chapter presents a mapping of the contemporary digital journalist's professional profile, highlighting the skills for ‘being’ a journalist, and ‘performing’ journalistic activities in the new century. This is based on meta-research conducted on the Scopus and Google Scholar databases, and the Capes Catalogue, for a longitudinal study of the bibliographical framework between 2000 and 2020, combined with the application of a questionnaire with 31 legacy and local digital media editors in Brazil. Evidence indicates that contemporary digital journalistic work is experiencing a trend towards platformization and surrounded by constant adaptability to new technologies, journalism is undergoing a crisis continuum, accentuated by the COVID-19 pandemic. With insecure work, and a context of datafication and algorithmization, the journalist needs to address the need for constant innovation and qualification, without neglecting the ethos of the profession. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.
ABSTRACT
The study focuses on educational policies, focusing on the teaching and learning process in the State of Tocantins, during the Covid-19 pandemic period. This is a research with a bibliographic approach, through the analysis of the pre- and post-pandemic period in education in Tocantins. The objective of the research is to analyze the educational indicators that impact the teaching and learning process and, consequently, the permanence and access to quality education. In view of the analysis, it is possible to affirm that there was an accentuation of educational/social inequality, when observing the data on dropouts/dropouts, age-grade distortion and failure in public schools. Covid-19 is an aggravating factor in the gap in teaching and learning, highlighting the need for post-pandemic actions to mitigate the impacts, especially in the context of public education.
ABSTRACT
Background: Newly drugs access for MM treatment still a challenge in some countries. One of the most available inductions for TE NDMM patients (pts) worldwide is cyclophosphamide (C), thalidomide (T) and dexamethasone (d)-(CTd). Dara the first anti- CD38, had been combined with VCd, VTd and VRd and markedly increased the depth and duration of the response. We hypothesized that Dara and CTd combination could be safe and allow deeper activity as an alternative protocol. Aims: The aims of this analysis were to evaluate Progression Free Survival (PFS) of Dara-CTd treatment and minimal residual disease (MRD) after one year of Dara maintenance. Primary endpoint of the study was to evaluate the VGPR after two consolidation cycles post-autologous stem cell transplantation (ASCT). Methods: This is a phase II, open-label single-center clinical trial. The main inclusion criteria were: TE NDMM, creatinine clearance > 30 ml/min, normal cardiac, renal and liver function and the Easter Cooperative Oncology Group (ECOG) performance status = 0 - 2. The protocol was Dara-CTd for up to four 28-day induction cycles: C-500mg oral (PO) on days 1,8 and 15, T at 100-200mg PO on days 1 to 28, (d) at 40mg PO on days 1,8,15 and 22 and Dara at 16mg/Kg/dose intravenous (IV) on days 1,8,15 and 22 during cycles 1 - 2 and every other week in cycles 3 - 4, followed by ASCT. All pts received up to four 28-day consolidation cycles that was started at D+30 after ASCT: Dara at 16mg/Kg and (d) at 40mg every other week, associated with T at 100mg PO on days 1 - 28. Dara at 16mg/Kg was used monthly as maintenance until progression or limiting toxicity. G-CSF was used for stem cell (SC) mobilization and plerixafor had been allowed whenever the pts need. The MRD was evaluated by next-generation flow (NGF) based and PET-CT was performed when the patient obtained NGF negativity or finished consolidation. PFS outcome was estimated using Kaplan-Meier method. All pts received antiviral, anti-pneumocystis and anti-thrombotic prophylaxis. Data cut-off was June 15, 2021. Results: The first pts was enrolled in November 2018. A total of 24 pts were included, the median age being 60 (range 37- 67 years), 23 (92%) were non-white, 5 (21%) had an R-ISS = 1, 12 (54%) had an R-ISS = 2 and 4 (16%), an R-ISS = 3. Six (25%) pts had high-risk chromosomal abnormalities [del17p, t(4;14) or t(14;16)]. To date, all pts have completed induction, 20 have received transplant and 17 have completed D+90 post-transplant assessment. No SC mobilization failure was observed, and six (30%) pts needed plerixafor use. By ITT analysis after a median follow up of 20 months the PFS at 12 and 18 months was 86%. No PFS difference was observed between different subgroups. Regarding response rates, after the end of induction (cycle 4), 19 (90%) of the pts obtained > PR and 8 (38%) obtained >VGPR, including three MRD negativity by NGF. 17 pts have completed two consolidation cycles after transplant and 94% obtained > VGPR as best response, 13 (76%) obtained MRD negativity by NGF and 10 (58%) had negative PET-CT. Seven (41%) pts had both flow and PET-CT negativity. Six pts completed one year of maintenance and five of them (83%) still MRD negativity by NGF. Four pts died from infection, two of them related with covid infection (one before transplant and one during maintenance). Another case post-transplant, considered not related to the investigational agent and one after consolidation, related to the investigational agent. Two pts have discontinued treatment due to progression - 1 before ASCT e 1 during maintenance. The most common adverse events (AEs) grades 3 and 4 were neutropenia (n = 12), infusion reaction (n = 7), neuropathy (n = 6), lymphopenia (n = 4), infection (n = 3), hypertension (n = 1) and rash (n = 1). Summary/Conclusion: The Daratumumab - CTd protocol is an active regimen capable of producing deep and sustainable responses and improve the PFS of NDMM TE pts with a favorable safety profile. Clinical trial information: NCT03792620. Disclosures: De Queiroz Crusoe: Janssen: Research Fund ng. Hungria: Sanofi: Honoraria, Other: Support for attending meetings/travel;Takeda: Honoraria;Abbvie: Honoraria;Amgen, BMS, Celgene, Janssen: Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Support for attending meetings/travel.
ABSTRACT
Background: Newly drugs access for MM treatment still a challenge. One of the available inductions for TE NDMM patients (pts) worldwide is cyclophosphamide (C), thalidomide (T) and dexamethasone (d)- (CTd). We hypothesized that the Daratumumab and CTd combo could be safe and allow deeper activity as an alternative protocol. Primary endpoint was to evaluate the VGPR after two consolidation cycles post-ASCT. Secondary endpoints were the ORR during all treatment phases and MRD, based on the IMWG criteria that includes the NGF by the EuroFlow® and PET-CT and the safety profile Method: This is a phase II, open-label single-center clinical trial. The main inclusion criteria were: TE NDMM, CrCl > 30 ml/min, normal cardiac, renal and liver function and the ECOG performance status = 0 - 2. The protocol was Dara-CTd for up to four 28-day induction cycles: C-500mg PO on days 1,8 and 15, T at 100-200mg PO on days 1 to 28, (d) at 40mg PO on days 1,8,15 and 22 and Dara at 16mg/Kg/dose IV- QW during cycles 1 - 2 and every other week in cycles 3 – 4, followed by ASCT. All pts received up to four 28-day consolidation cycles that was started at D+30 after ASCT: Dara and (d) at 40mg every other week, associated with T at 100mg PO on days 1 - 28. Dara was used monthly as maintenance until progression or limiting toxicity. G-CSF was used for stem cell (SC) mobilization and plerixafor if needed. All pts received anti(viral, pneumocystis and thrombotic) prophylaxis. Results: A total of 21 pts were included, the median age being 56 (range 37 – 67 years), 19 (90%) were non-white, 3 (14%) had an R-ISS = 1, 12 (57%) had an R-ISS = 2 and 3 (14%), an R-ISS = 3. Five (24%) pts had HR [del17p, t(4;14) or t(14;16)]. To date, all pts have completed induction, 19 have received transplant and 17 have completed D+90 post-transplant assessment. No SC mobilization failure was observed, and five (26%) pts needed plerixafor use. In an ITT analysis, after the end of induction (cycle 4), 19 (90%) of the pts obtained?> PR and 8 (38%) obtained >VGPR, including three MRD negativity by NGF. 17 pts have completed two consolidation cycles after transplant and 94% obtained?> VGPR, 12 (70%) obtained MRD negativity by NGF and nine (53%) had negative PET-CT. Seven (41%) pts had both flow and PET-CT negativity. Three pts died from infection, one before transplant because of Covid, one on post-transplant, considered not related to the investigational agent, and another after consolidation, related to the investigational agent. The most common nonhematological AEs grades 3 and 4 before ASCT were neuropathy (n = 6), infusion reaction (n = 7), infection (n = 2), hypertension (n = 1) and rash (n = 1). Conclusion: This is the first study that combined Dara with CTd as induction for TE NDMM pts. This present data has shown that the association of Dara-CTd achieved the primary end point once > 90% of the pts achieved VGPR after two consolidations cycles, and safety profile was acceptable. Clinical trial information: NCT03792620.
ABSTRACT
Background : Venous thromboembolism (VTE) is an important cause of morbimortality in cancer patients. Comprehensive management of VTE, includes not only its effective its treatment, but also identification of patients who will benefit from thromboprophylaxis. Khorana score is the main validated tool for VTE risk-stratification. Aims : Develop a predictive model of VTE in ambulatory cancer patients, combining thrombosis biomarkers ( D-dimers and thrombin generation potential) with Khorana model. Methods : This is a prospective observational study that Includes patients with a cancer diagnosis, proposed for anti-tumour treatments (chemotherapy, immunotherapy or targeted therapies). Patients with major bleeding in the last 3 months, major surgery in the last 28 days, on anticoagulation/antithrombotic therapy were excluded. Patients' disease characteristics, blood count values and thrombosis biomarkers were collected at baseline. The primary endpoint is the occurrence of symptomatic or incidental VTE at 6 and 12 months. The study was approved by the local ethics committee. Informed consent was obtained prior to study inclusion. Results : From April-December 2019, 211 patients were enrolled, 171 analysed (40 were excluded). Median age was 56 [21-81], 53% were female. The majority had breast (22%, n = 38), colorectal (20%, n = 34) and gastric/gastroesophagic (14%, n = 24) malignancies, 68% had advanced disease (stage III-IV). The majority initiated chemotherapy+/-targeted therapies (95%, n = 163). At 6 months, 9 patients (5.3%) were diagnosed with VTE (4 pulmonary embolisms, 3 catheter-related and 2 deep venous thrombosis), 56% ( n = 5) were incidental findings on exams. VTE was more frequent in metastatic or locally advanced solid cancers (78%, n = 7), and in gastric/gastroesophagic/ biliary (44%, n = 4) and coloretal (22%, n = 2). At 12 months VTE was present in 8.8% ( n = 15). Conclusions : Recruitment achieved 74% by December 2020, lower than expected due to COVID-19 pandemics. This study is ongoing and will result in a comprehensive risk model adapted to new realities taking into account the diversity of anti-tumour treatments available.
ABSTRACT
COVID 19 disrupted food supply chains worldwide. Existing problems, such as food and nutrition insecurity, increased exponentially. It has become imperative to move to a more sustainable and equitable food system. In this sense, the challenge in researching food losses and waste (FLW) and proposing solutions mobilizes transdisciplinary approaches and processes to transform food supply chains in an effective manner. Understanding how much food we produce and consume is no easy task. So many different geographical, cultural and societal contexts and levels of economic development and urbanization result in quantitative and qualitative limitations © RAE ;São Paulo
ABSTRACT
Background: Newly drugs access for MM treatment still a challenge in some countries. One of the most available inductions for TE NDMM patients (pts) worldwide is cyclophosphamide (C), thalidomide (T) and dexamethasone (d)- (CTd). Dara the first anti- CD38, had been combined with VCd, VTd and VRd and markedly increased the depth and duration of the response. We hypothesized that the combination of Dara and CTd could be safe and allow deeper activity as an alternative protocol. Aims: The primary endpoint was to evaluate the VGPR after two consolidation cycles post-autologous stem cell transplantation (ASCT). Secondary endpoints were the overall response rate during all treatment phases and minimal residual disease (MRD), based on the International Myeloma Working Group (IMWG) criteria that includes the next-generation flow (NGF) by the EuroFlow. and PET-CT and the safety profile. Methods: This is a phase II, open-label single-center clinical trial. The main inclusion criteria were: TE NDMM, creatinine clearance ≥ 30 ml/min, normal cardiac, renal and liver function and the Easter Cooperative Oncology Group (ECOG) performance status = 0 - 2. The protocol was Dara-CTd for up to four 28-day induction cycles: C-500mg oral (PO) on days 1,8 and 15, T at 100-200mg PO on days 1 to 28, (d) at 40mg PO on days 1,8,15 and 22 and Dara at 16mg/Kg/dose intravenous (IV) on days 1,8,15 and 22 during cycles 1 - 2 and every other week in cycles 3 - 4, followed by ASCT. All pts received up to four 28-day consolidation cycles that was started at D+30 after ASCT: Dara at 16mg/Kg and (d) at 40mg every other week, associated with T at 100mg PO on days 1 - 28. Dara at 16mg/Kg was used monthly as maintenance until progression or limiting toxicity. G-CSF was used for stem cell (SC) mobilization and plerixafor had been allowed whenever the pts need. All pts received antiviral, anti-pneumocystis and anti-thrombotic prophylaxis. Results: The first pts was enrolled in November 2018. A total of 21 pts were included, the median age being 56 (range 37 - 67 years), 19 (90%) were non-white, 3 (14%) had an R-ISS = 1, 12 (57%) had an R-ISS = 2 and 3 (14%), an R-ISS = 3. Five (24%) pts had high-risk chromosomal abnormalities [del17p, t(4;14) or t(14;16)]. To date, all pts have completed induction, 19 have received transplant and 17 have completed D+90 post-transplant assessment. No SC mobilization failure was observed, and five (26%) pts needed plerixafor use. In an intention to treatment analysis, after the end of induction (cycle 4), 19 (90%) of the pts obtained > PR and 8 (38%) obtained ≥VGPR, including three MRD negativity by NGF. 17 pts have completed two consolidation cycles after transplant and 94% obtained ≥ VGPR as best response, 12 (70%) obtained MRD negativity by NGF and nine (53%) had negative PET-CT. Seven (41%) pts had both flow and PET-CT negativity. Three pts died from infection, one before transplant because of Covid infection, on post-transplant, considered not related to the investigational agent, and another after consolidation, related to the investigational agent. The most common nonhematological adverse events (AEs) grades 3 and 4 before ASCT were neuropathy (n = 6), infusion reaction (n = 7), infection (n = 2), hypertension (n = 1) and rash (n = 1). Summary/Conclusion: This is the first study that combined Dara with CTd as induction for TE NDMM pts. This present data has shown that the association of Dara-CTd achieved the primary end point once ≥ 90% of the pts achieved VGPR after two consolidations cycles, and safety profile was acceptable. Clinical trial information: NCT03792620.
ABSTRACT
This article aims to quantify and qualify the information circulating in social media groups about COVID-19, the subjects covered in posts, as well as the possible relations with other subjects, events or social events, in order to generate a representative panorama of perception and social reaction to the coronavirus pandemic. For this, statistical techniques, data mining and machine learning are used to the characterization, pattern detection, and grouping of textual data. The experiments are carried out on a dataset of textual data extracted from a Brazilian public group about COVID-19 (SARS-cov-2) of the social network Facebook. Statistical analyzes are crossed with data on the advance of the number of infected, and with specific political-social events, revealing variations and influences in terms of participation and engagement in the analyzed group. In addition, through the results obtained by the clustering method used, two main groups of posts are detected, the first presenting a content pattern geared to governmental issues, and the second to personal issues. The results achieved still allow a reflection on the possible social impacts of the creation or absence of public policies to deal with the COVID-19 pandemic.